Myc-associated zinc-finger protein promotes clear cell renal cell carcinoma progression through transcriptional activation of the MAP2K2-dependent ERK pathway

Abstract Background The dysfunction of myc-related zinc finger protein (MAZ) has been proven to contribute to tumorigenesis and development of multiple cancer types.However, the biological roles and clinical significance of MAZ in clear cell renal carcinoma (ccRCC) remain unclear.Methods MAZ expression was examined in ccRCC and normal kidney tissue

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Analysis of structural changes in OWL 2 ontologies

The urgency of the discussed problem is caused by the need to develop web ontologies in a distributed collaborative manner.One of the tasks is the ontology version comparison and change analysis.The developers require processed information on ontology changes in order to collaborate more efficiently (what entities were changes, added or removed fro

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